RNA splicing capability of live neuronal dendrites.
AuthorsGlanzer J, Miyashiro KY, Sul JY, Barrett L, Belt B, Haydon P, Eberwine J,
JournalProc Natl Acad Sci U S A
PubMed ID16275927
Dendrites are specialized extensions of the neuronal soma that contain components of the cellular machinery involved in RNA and protein metabolism. Several dendritically localized proteins are associated with the precursor-mRNA (pre-mRNA) splicing complex, or spliceosome. Although some spliceosome-related, RNA-binding proteins are known to subserve separate cytoplasmic functions when moving between ... More