Isolation, characterization and propagation of mitotically active germ cells from adult mouse and human ovaries.
AuthorsWoods DC, Tilly JL
JournalNat Protoc
PubMed ID23598447
Accruing evidence indicates that production of new oocytes (oogenesis) and their enclosure by somatic cells (folliculogenesis) are processes not limited to the perinatal period in mammals. Endpoints ranging from oocyte counts to genetic lineage tracing and transplantation experiments support a paradigm shift in reproductive biology involving active renewal of oocyte-containing ... More