Differential effects of flavonoids on barrier integrity in human intestinal caco-2 cells.
AuthorsNoda S, Tanabe S, Suzuki T
JournalJ Agric Food Chem
PubMed ID22506771
'Flavonoids, present in fruits, vegetables, and teas, provide beneficial effects for our health. We investigated the effect of a number of flavonoids on tight junction (TJ) barrier integrity in human intestinal Caco-2 cells. Transepithelial electrical resistance (TER; a TJ integrity marker) across cell monolayers was measured in cells incubated with ... More
ICC pacing mechanisms in intact mouse intestine differ from those in cultured or dissected intestine.
AuthorsBoddy G, Bong A, Cho W, Daniel EE,
JournalAm J Physiol Gastrointest Liver Physiol
PubMed ID14656713
Pacing of mouse intestine is driven by spontaneous activity of a network of interstitial cells of Cajal in the myenteric plexus (ICC-MP). So far, highly dissected circular muscle (CM) strips from control and mutant mice lacking ICC-MP and isolated, cultured ICC from newborn control mice were used to analyze its ... More