Genome-wide analysis of promoter methylation associated with gene expression profile in pancreatic adenocarcinoma.
AuthorsVincent A, Omura N, Hong SM, Jaffe A, Eshleman J, Goggins M,
JournalClin Cancer Res
PubMed ID21610144
The goal of this study was to comprehensively identify CpG island methylation alterations between pancreatic cancers and normal pancreata and their associated gene expression alterations. We employed methylated CpG island amplification followed by CpG island microarray, a method previously validated for its accuracy and reproducibility, to analyze the methylation profile ... More