Regulation and possible function of beta-catenin in human monocytes.
AuthorsThiele A, Wasner M, Müller C, Engeland K, Hauschildt S,
JournalJ Immunol
PubMed ID11739494
In this study, we demonstrate that adherence factors, serum constituents, LPS, and zymosan are capable of inducing a cellular accumulation of beta-catenin in human monocytes. Whereas adherence-dependent accumulation of beta-catenin can be blocked by wortmannin, an inhibitor of phosphatidylinositol 3-kinase, accumulation induced by the remaining stimuli cannot be prevented by ... More