Nuclear localisation of LASP-1 correlates with poor long-term survival in female breast cancer.
AuthorsFrietsch JJ, Grunewald TG, Jasper S, Kammerer U, Herterich S, Kapp M, Honig A, Butt E,
JournalBr J Cancer
PubMed ID20461080
LIM and SH3 protein 1 (LASP-1) is a nucleo-cytoplasmatic signalling protein involved in cell proliferation and migration and is upregulated in breast cancer in vitro studies have shown that LASP-1 might be regulated by prostate-derived ETS factor (PDEF), p53 and/or LASP1 gene amplification. This current study analysed the prognostic significance ... More