Control of hippocampal dendritic spine morphology through ephrin-A3/EphA4 signaling.
AuthorsMurai KK, Nguyen LN, Irie F, Yamaguchi Y, Pasquale EB,
JournalNat Neurosci
PubMed ID12496762
'Communication between glial cells and neurons is emerging as a critical parameter of synaptic function. However, the molecular mechanisms underlying the ability of glial cells to modify synaptic structure and physiology are poorly understood. Here we describe a repulsive interaction that regulates postsynaptic morphology through the EphA4 receptor tyrosine kinase ... More