BMP7 and SHH regulate Pax2 in mouse retinal astrocytes by relieving TLX repression.
AuthorsSehgal R, Sheibani N, Rhodes SJ, Belecky Adams TL,
JournalDev Biol
PubMed ID19505455
'Pax2 is essential for development of the neural tube, urogenital system, optic vesicle, optic cup and optic tract. In the eye, Pax2 deficiency is associated with coloboma, a loss of astrocytes in the optic nerve and retina, and abnormal axonal pathfinding of the ganglion cell axons at the optic chiasm. ... More