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Invitrogen
HSP90 beta Monoclonal Antibody (H9010)
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FIGURE: 1 / 30
HSP90 beta Antibody (37-9400) in ICC/IF
Immunofluorescence analysis of Hsp90 beta was done on 70% confluent log phase HeLa cells. The cells were fixed with 4% paraformaldehyde for 10 minutes, permeabilized with 0.1% Triton™ X-100 for 10 minutes, and blocked with 1% BSA for 1 hour at room temperature. The cells were labeled with Hsp90 beta (H9010) Mouse Monoclonal Antibody (Product # 37-9400) at 1:250 dilution in 0.1% BSA and incubated for 3 hours... View More
Product Details
37-9400
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Chicken,
Human,
Mouse,
Rabbit
Published species
C. elegans,
Human,
Mouse,
Rat,
Xenopus
Host/Isotype
Mouse
/ IgG2a, kappa
Class
Monoclonal
Type
Antibody
Clone
H9010
Immunogen
Recombinant human HSP90-beta
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
0.1% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
Heat shock proteins (HSP) are expressed in response to various biological stresses, including heat. HSP90 is a 90 kDa protein that is induced under stress conditions, but is also one of the most abundant cellular proteins found under non-stress conditions. HSP90 proteins are highly conserved molecular chaperones that have key roles in signal transduction, protein folding, protein degradation, and morphologic evolution. HSP90 proteins normally associate with other cochaperones and play important roles in folding newly synthesized proteins or stabilizing and refolding denatured proteins after stress. HSP90 has been found to be associated with a number of other intracellular proteins, including steroid receptors, actin, tubulin, aryl hydrocarbon (Ah) receptor, and some kinases.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Heat shock 84 kDa; heat shock 90kD protein 1, beta; heat shock 90kDa protein 1, beta; Heat shock protein; heat shock protein 1, beta; heat shock protein 90 beta; heat shock protein 90 kDa; heat shock protein 90kDa alpha (cytosolic), class B member 1; heat shock protein 90kDa alpha family class B member 1; Heat shock protein family C member 3; Heat shock protein HSP 90-beta; heat shock protein, 84 kDa 1; HSP; HSP 84; HSP 90; hsp90 beta; HSP90-beta; retinal degeneration slow protein; RP1-302G2.1; TSTA; Tumor-specific transplantation 84 kDa antigen
Gene Aliases: 90kDa; AL022974; C81438; D6S182; HSP84; Hsp84-1; Hsp90; HSP90AB1; HSP90B; HSPC2; HSPC3; HSPCB
UniProt ID: (Rabbit) P30947, (Human) P08238, (Mouse) P11499
Entrez Gene ID: (Chicken) 396188, (Rabbit) 100358690, (Human) 3326, (Mouse) 15516
ATP binding
protein dimerization activity
unfolded protein binding
UTP binding
CTP binding
double-stranded RNA binding
protein binding
GTP binding
sulfonylurea receptor binding
protein kinase regulator activity
kinase binding
protein kinase binding
MHC class II protein complex binding
nitric-oxide synthase regulator activity
TPR domain binding
dATP binding
histone deacetylase binding
ion channel binding
poly(A) RNA binding
cadherin binding involved in cell-cell adhesion
nucleotide binding
Hsp90 family chaperone
protein folding
positive regulation of transforming growth factor beta receptor signaling pathway
negative regulation of proteasomal ubiquitin-dependent protein catabolic process
negative regulation of cell cycle arrest
negative regulation of transforming growth factor beta activation
placenta development
response to unfolded protein
response to salt stress
virion attachment to host cell
regulation of protein ubiquitination
positive regulation of protein binding
positive regulation of phosphoprotein phosphatase activity
positive regulation of protein import into nucleus, translocation
Fc-gamma receptor signaling pathway involved in phagocytosis
negative regulation of neuron apoptotic process
positive regulation of nitric oxide biosynthetic process
positive regulation of cell size
protein stabilization
regulation of interferon-gamma-mediated signaling pathway
regulation of type I interferon-mediated signaling pathway
cellular response to interleukin-4
cellular response to organic cyclic compound
positive regulation of protein serine/threonine kinase activity
fibril organization
cell-cell adhesion
regulation of cellular response to heat
response to stress
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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