E2A-positive gastric MALT lymphoma has weaker plasmacytoid infiltrates and stronger expression of the memory B-cell-associated miR-223: possible correlation with stage and treatment response.
AuthorsLiu TY, Chen SU, Kuo SH, Cheng AL, Lin CW,
JournalMod Pathol
PubMed ID20802470
'Extranodal marginal-zone lymphoma of mucosa-associated lymphoid tissue of the stomach (gastric MALT lymphoma) is derived from memory B cells of the marginal zone. Normal memory B cells do not express markers of germinal-center B cells, such as E2A (immunoglobulin enhancer-binding factor E12/E47), B-cell chronic lymphocytic leukemia/lymphoma 6 (BCL6), or activation-induced ... More
The role of activation-induced cytidine deaminase expression in gastric adenocarcinoma.
AuthorsBatsaikhan BE, Kurita N, Iwata T, Sato H, Yoshikawa K, Takasu C, Kashihara H, Matsumoto N, Ishibashi H, Shimada M,
Journal
PubMed ID24511045
Gastric adenocarcinoma is one of the most common malignant tumors and the leading cause of malignancy-related death worldwide. Studies have reported overexpression of activation-induced cytidine deaminase (AID) and protein kinase c iota (PKCi) proteins showing involvement in the regulation of carcinogenesis. In the present study, we investigated the expression of ... More