Differential expression and subcellular localization of claudin-7, -8, -12, -13, and -15 along the mouse intestine.
AuthorsFujita H, Chiba H, Yokozaki H, Sakai N, Sugimoto K, Wada T, Kojima T, Yamashita T, Sawada N,
JournalJ Histochem Cytochem
PubMed ID16651389
'Among tight-junction proteins, claudins, which play a key role in paracellular transport across epithelia, claudins 1 to 5 are expressed in the intestine, and changes in their abundance and/or distribution are considered to contribute to various gastrointestinal diseases. We investigated, by reverse transcription-PCR, immunoblot, and immunofluorescence analyses, which other claudin ... More
Claudins 6, 9, and 13 are developmentally expressed renal tight junction proteins.
AuthorsAbuazza G, Becker A, Williams SS, Chakravarty S, Truong HT, Lin F, Baum M,
JournalAm J Physiol Renal Physiol
PubMed ID16774906
The adult proximal tubule is a low-resistance epithelium where there are high rates of both active transcellular and passive paracellular NaCl transport. We have previously demonstrated that the neonatal rabbit and rat proximal tubule have substantively different passive paracellular transport properties than the adult proximal tubule, which results in a ... More