Function of caspase-14 in trophoblast differentiation.
AuthorsWhite LJ, Declercq W, Arfuso F, Charles AK, Dharmarajan AM,
JournalReprod Biol Endocrinol
PubMed ID19747408
Within the human placenta, the cytotrophoblast consists of a proliferative pool of progenitor cells which differentiate to replenish the overlying continuous, multi-nucleated syncytiotrophoblast, which forms the barrier between the maternal and fetal tissues. Disruption to trophoblast differentiation and function may result in impaired fetal development and preeclampsia. Caspase-14 expression is ... More