引用和文献 (2)

#PTRCHIS A,B,C KIT

Name: #PTRCHIS A,B,C KIT
SKU: 430025

货号 430025

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#PTRCHIS A,B,C KIT

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引用和文献 (2)

引用和文献

Abstract

Inhibitory Potency and Specificity of Subtilase-like Pro-protein Convertase (SPC) Prodomains.

Authors: Fugere Martin; Limperis Polizois C; Beaulieu-Audy Veronique; Gagnon Frederic; Lavigne Pierre; Klarskov Klaus; Leduc Richard; Day Robert;

Journal:J Biol Chem

PubMed ID:11723118

'The SPCs (subtilisin-like pro-protein convertases) are a family of enzymes responsible for the proteolytic processing of numerous precursor proteins of the constitutive and regulated secretory pathways. SPCs are themselves synthesized as inactive zymogens. Activation of SPCs occurs via the intramolecular autocatalytic removal of the prodomain. SPC prodomains have been proposed ... More

Moe1, a conserved protein in Schizosaccharomyces pombe, interacts with a Ras effector, Scd1, to affect proper spindle formation.

Authors:Chen CR, Li YC, Chen J, Hou MC, Papadaki P, Chang EC

Journal:Proc Natl Acad Sci U S A

PubMed ID:9892665

In fission yeast, Scd1/Ral1 is a putative guanine nucleotide exchange factor for Cdc42sp and also acts as a Ras1 effector necessary for the regulation of cytoskeleton organization. In this study, we have characterized a protein, Moe1, that binds directly to Scd1. A moe1 null (Delta) mutant exhibits numerous phenotypes indicative ... More