引用和文献 (4)

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引用和文献 (4)

引用和文献

Abstract

Mutational analysis of mammalian translation initiation factor 5 (eIF5): role of interaction between the beta subunit of eIF2 and eIF5 in eIF5 function in vitro and in vivo

Authors:Das S, Maitra U

Journal:Mol Cell Biol

PubMed ID:10805737

'Eukaryotic translation initiation factor 5 (eIF5) interacts with the 40S initiation complex (40S-eIF3-AUG-Met-tRNA(f)-eIF2-GTP) to promote the hydrolysis of ribosome-bound GTP. eIF5 also forms a complex with eIF2 by interacting with the beta subunit of eIF2. In this work, we have used a mutational approach to investigate the importance of eIF5-eIF2beta ... More

Escherichia coli TehB requires S-adenosylmethionine as a cofactor To mediate tellurite resistance.

Authors:Liu M, Turner RJ, Winstone TL, Saetre A, Dyllick-Brenzinger M, Jickling G, Tari LW, Weiner JH, Taylor DE

Journal:J Bacteriol

PubMed ID:11053398

The Escherichia coli chromosomal determinant for tellurite resistance consists of two genes (tehA and tehB) which, when expressed on a multicopy plasmid, confer resistance to K(2)TeO(3) at 128 &mgr;g/ml, compared to the MIC of 2 &mgr;g/ml for the wild type. TehB is a cytoplasmic protein which possesses three conserved motifs ... More

A novel chromodomain protein, pdd3p, associates with internal eliminated sequences during macronuclear development in Tetrahymena thermophila.

Authors:Nikiforov MA, Gorovsky MA, Allis CD

Journal:Mol Cell Biol

PubMed ID:10805754

Conversion of the germ line micronuclear genome into the genome of a somatic macronucleus in Tetrahymena thermophila requires several DNA rearrangement processes. These include (i) excision and subsequent elimination of several thousand internal eliminated sequences (IESs) scattered throughout the micronuclear genome and (ii) breakage of the micronuclear chromosomes into hundreds ... More

The mouse Dazla gene encodes a cytoplasmic protein essential for gametogenesis.

Authors:Ruggiu M, Speed R, Taggart M, McKay SJ, Kilanowski F, Saunders P, Dorin J, Cooke HJ

Journal:Nature

PubMed ID:9288969

RBM and DAZ/SPGY are two families of genes located on the Y chromosome that encode proteins containing RNA-binding motifs, and both have been described as candidate human spermatogenesis genes. Transmission of deletions from father to son has been observed in the case of DAZ, but neither gene family has been ... More