mom identifies a receptor for the Drosophila JAK/STAT signal transduction pathway and encodes a protein distantly related to the mammalian cytokine receptor family.
Authors Chen Hua-Wei; Chen Xiu; Oh Su-Wan; Marinissen Maria J; Gutkind J Silvio; Hou Steven X;
JournalGenes Dev
PubMed ID11825879
The JAK/STAT signal transduction pathway controls numerous events in Drosophila melanogaster development. Receptors for the pathway have yet to be identified. Here we have identified a Drosophila gene that shows embryonic mutant phenotypes identical to those in the hopscotch (hop)/JAK kinase and marelle (mrl)/Stat92e mutations. We named this gene master ... More