Mitochondrial DNA toxicity compromises mitochondrial dynamics and induces hippocampal antioxidant defenses.
AuthorsLauritzen KH, Cheng C, Wiksen H, Bergersen LH, Klungland A,
JournalDNA Repair (Amst)
PubMed ID21550321
'Mitochondria are highly dynamic organelles that can be actively transported within the cell to satisfy local requirements. They are vital for providing cellular energy, but are also an important endogenous source of reactive oxygen species. The distribution of mitochondria is particularly important for neurons because of the morphological complexity of ... More