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          • Primary Antibodies ›
          • CD160 Antibodies

          Invitrogen

          CD160 Monoclonal Antibody (BY55), eFluor™ 660, eBioscience™

          3个已发表图片
          3 篇参考文献
          查看其他31个CD160抗体

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          Cite CD160 Monoclonal Antibody (BY55), eFluor™ 660, eBioscience™

          Additional Information:
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          • 抗体检测数据 (1)
          • 已发表图片 (3)
          CD160 Antibody in Flow Cytometry (Flow)
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          CD160 Antibody in Flow Cytometry (Flow)
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          图: 1 / 4

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          CD160 Antibody (50-1609-42) in Flow

          Staining of normal human peripheral blood cells with Anti-Human CD56 (NCAM) FITC (Product # 11-0569) and Mouse IgM Isotype Control eFluor® 660 (Product # 50-4752-82) (left) or Anti-Human CD160 eFluor® 660 (right). Cells in the lymphocyte gate were used for analysis. {{ $ctrl.currentElement.advancedVerification.fullName }} 验证信息 View more
          已发表图片由___提供 benchsci-logo
          PMID: {{$ctrl.currentElement.benchSciPubmedId}}
          查看产品

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          CD160 Antibody in Flow Cytometry (Flow)
          CD160 Antibody in Flow Cytometry (Flow)
          CD160 Antibody in Flow Cytometry (Flow)
          CD160 Antibody in Flow Cytometry (Flow)

          产品信息

          50-1609-42

          应用
          建议稀释比
          已发表文章

          流式细胞分析 (Flow)

          5 µL (0.25 µg)/test
          查看3篇已发表文章 3篇已发表文章
          产品规格

          种属反应

          Human

          宿主/亚型

          Mouse / IgM

          推荐的同型对照

          Mouse IgM Isotype Control (11E10), eFluor™ 660, eBioscience™

          分类

          Monoclonal

          类型

          Antibody

          克隆号

          BY55

          偶联物

          eFluor™ 660 eFluor™ 660 eFluor™ 660
          • Alexa Fluor 488 
          • PE 
          • Request custom conjugation

          激发/发射光谱

          651/668 nm 查看光谱 spectra

          形式

          Liquid

          浓度

          5 µL/Test

          纯化类型

          Affinity chromatography

          保存液

          PBS, pH 7.2, with BSA

          内含物

          0.09% sodium azide

          保存条件

          4°C, store in dark, DO NOT FREEZE!

          运输条件

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2574185

          产品详细信息

          Description: This BY55 monoclonal antibody reacts with human CD160, a member of the immunoglobulin superfamily expressed on natural killer cells, natural killer T cells, activated and/or memory CD4 and CD8 T cells, gamma delta T cells, and intraepithelial cells. CD160 has been reported to bind herpes virus entry mediator (HVEM) in a complex with LIGHT and BTLA to deliver an inhibitory signal to CD4 T cells that abrogates proliferation and cytokine production. Three alternative splice variants of CD160 have also been identified in natural killer cells.

          Applications Reported: This BY55 antibody has been reported for use in flow cytometric analysis.

          Applications Tested: This BY55 antibody has been pre-titrated and tested by flow cytometric analysis of normal human peripheral blood cells. This can be used at 5 µL (0.25 µg) per test. A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test.

          eFluor® 660 is a replacement for Alexa Fluor® 647. eFluor® 660 emits at 659 nm and is excited with the red laser (633 nm). Please make sure that your instrument is capable of detecting this fluorochome.

          Excitation: 633-647 nm; Emission: 668 nm; Laser: Red Laser.

          Filtration: 0.2 µm post-manufacturing filtered.

          靶标信息

          CD160 is a receptor showing broad specificity for both classical and non-classical MHC class I molecules. CD160 is expressed at the cell surface as a tightly disulfide-linked multimer. It is involved in cell proliferation, cell surface receptor signaling pathways, cellular defense response, and regulation of immune response.

          仅用于科研。不用于诊断过程。未经明确授权不得转售。

          How to use the Panel Builder

          Watch the video to learn how to use the Invitrogen Flow Cytometry Panel Builder to build your next flow cytometry panel in 5 easy steps.

          生物信息学

          蛋白别名: CD160; CD160 antigen; CD160-delta Ig; immunoglobulin superfamily member; natural killer cell receptor; Natural killer cell receptor BY55; natural killer cell receptor, immunoglobulin superfamily member; receptor

          查看更多 收起

          基因别名: BY55; CD160; NK1; NK28

          查看更多 收起

          UniProt ID: (Human) O95971

          查看更多 收起

          Entrez Gene ID: (Human) 11126

          查看更多 收起

          功能
          transmembrane signaling receptor activity receptor binding protein binding kinase binding MHC class I protein complex binding MHC class I receptor activity MHC class Ib receptor activity activating MHC class I receptor activity
          参与通路
          angiogenesis positive regulation of cytokine production adaptive immune response immune system process mucosal immune response positive regulation of natural killer cell mediated immunity positive regulation of natural killer cell cytokine production regulation of adaptive immune response positive regulation of natural killer cell mediated immune response to tumor cell negative regulation of angiogenesis T cell costimulation positive regulation of interferon-gamma production positive regulation of natural killer cell degranulation protein kinase B signaling innate immune response positive regulation of natural killer cell mediated cytotoxicity defense response to Gram-negative bacterium negative regulation of T cell receptor signaling pathway negative regulation of CD4-positive, alpha-beta T cell costimulation negative regulation of adaptive immune memory response positive regulation of endothelial cell apoptotic process
          It has to be done as per old AB suggested Products section.

          Disclaimer

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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

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          只要您发现Invitrogen抗体在实验中的表现与网站或说明书的所述内容不符,您即可享受免费退换货服务。*

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