Immune interferon induces the receptor for monomeric IgG1 on human monocytic and myeloid cells.
AuthorsPerussia B, Dayton ET, Lazarus R, Fanning V, Trinchieri G
JournalJ Exp Med
PubMed ID6225822
'We report here that FcR for human monomeric IgG1 can be induced on cells of myeloid origin cultured in the presence of IFN gamma for 8 h. Supernatant fluids from cultures of lymphocytes infected with a variety of viruses or cocultured with cell lines have the same FcR enhancing effect ... More
IgG Fc receptors.
AuthorsRavetch JV, Bolland S
JournalAnnu Rev Immunol
PubMed ID11244038
'Since the description of the first mouse knockout for an IgG Fc receptor seven years ago, considerable progress has been made in defining the in vivo functions of these receptors in diverse biological systems. The role of activating Fc gamma Rs in providing a critical link between ligands and effector ... More
Roles of Fc receptors in autoimmunity.
AuthorsTakai T
JournalNat Rev Immunol
PubMed ID12154377
FcgammaRI-deficient mice show multiple alterations to inflammatory and immune responses.
AuthorsBarnes N, Gavin AL, Tan PS, Mottram P, Koentgen F, Hogarth PM
JournalImmunity
PubMed ID11911823
The inactivation of the mouse high-affinity IgG Fc receptor FcgammaRI resulted in a wide range of defects in antibody Fc-dependent functions. These studies showed the primary importance of FcgammaRI in endocytosis of monomeric IgG, kinetics, and extent of phagocytosis of immune complexes, in macrophage-based ADCC, and in immune complex-dependent antigen ... More
Neutrophils express the high affinity receptor for IgG (Fc gamma RI, CD64) after in vivo application of recombinant human granulocyte colony-stimulating factor.
AuthorsRepp R, Valerius T, Sendler A, Gramatzki M, Iro H, Kalden JR, Platzer E
JournalBlood
PubMed ID1714327
Fc receptors are important effector molecules of neutrophilic granulocytes (polymorphonuclear neutrophils [PMN]), connecting phagocytic cells and the specific immune response. Neutrophils from healthy donors express the low-affinity receptors for IgG Fc gamma RII (CD32) and Fc gamma RIII (CD16), but not the high-affinity receptor Fc gamma RI (CD64). The latter ... More