Axiom™ 绵羊基因分型芯片

The Applied Biosystems Axiom Ovine Genotyping Array provides the power and resolution to enable a wide range of applications in sheep breeding, including breed assignment, parentage verification and discovery, and traceability and monitoring of polymorphisms of known large effect. The 11,000 markers on the array facilitate highly accurate imputation up to a higher density panel (e.g., 50K panel) The Axiom Ovine Genotyping Array includes 88 single nucleotide polymorphisms (SNPs) proposed by the International Sheep Genomics Consortium (ISGC) for parentage verification.

Features include:
• Expert design—developed in collaboration with Donagh Berry at Teagasc, Animal and Grassland Research and Innovation Center, Ireland
• Exceptionally high quality SNPs with excellent call and concordance rates across platforms and laboratories
• Includes SNPs for parentage as well as other traits including scrapie
• Compatible with Sheep Consortium 15K arrays and thus with previous studies

Applications
• Parentage verification and discovery
• Accurate genomic evaluations
• Genome-wide associations following accurate imputation to higher density panel
• Breed assignment
• Monitoring of major genes
• Aneuploidy detection—early detection of such abnormalities enables identification of animals that are not suitable parents for the next generation • Measurement of genetic diversity including calculation of genomic inbreeding statistics
• Mating designs
• Traceability

Required products
GeneChip Command Console Software
GeneTitan Multi-Channel Instrument
Axiom Analysis Suite Software