Cell allocation in mammalian CNS formation: evidence from murine interspecies aggregation chimeras.
AuthorsGoldowitz D
JournalNeuron
PubMed ID2642015
'The central nervous system of murine intraspecies chimeras generally consists of an apparently random mixture of neurons derived from each of the parental genotypes. In this study, interspecies mouse chimeras were examined, and an analysis of the parental genotype donation to the chimeric CNS revealed large clusters of like-genotype neurons ... More
BDNF mRNA expression is increased in adult rat forebrain after limbic seizures: temporal patterns of induction distinct from NGF.
AuthorsIsackson PJ, Huntsman MM, Murray KD, Gall CM
JournalNeuron
PubMed ID2054188
We have localized brain-derived neurotrophic factor (BDNF) mRNA in rat brain and examined its regulation by seizure activity. In situ hybridization of BDNF 35S-cRNA most prominently labeled neurons in hippocampal stratum pyramidale and stratum granulosum, superficial olfactory cortex, pyramidal cell layers of neocortex, amygdala, claustrum, endopiriform nucleus, anterior olfactory nucleus, ... More