Mean platelet volume and integrin alleles correlate with levels of integrins a(IIb)ß(3) and a(2)ß(1) in acute coronary syndrome patients and normal subjects.
AuthorsKunicki TJ, Williams SA, Nugent DJ, Yeager M
JournalArterioscler Thromb Vasc Biol
PubMed ID22015659
The interindividual variation in platelet a(2)ß(1) exceeds a 2-fold variance in platelet a(IIb)ß(3) level. Our objective was to parse the contribution of mean platelet volume (MPV) and integrin gene alleles to this variation in large cohorts of patients with acute coronary syndrome (ACS) and normal subjects. ... More