Retinol dehydrogenase 13 protects the mouse retina from acute light damage.
AuthorsWang H, Cui X, Gu Q, Chen Y, Zhou J, Kuang Y, Wang Z, Xu X,
JournalMol Vis
PubMed ID22605914
To investigate whether retinol dehydrogenase 13 (RDH13) can protect the retina from acute light-induced damage. We generated Rdh13 knockout mice using molecular biologic methods and assessed the associated morphological and functional changes under room-light conditions by hematoxylin-eosin (H&E), transmission electron microscopy (TEM), and scotopic electroretinography. Then, the light-damage model was ... More