ErbB2 receptor controls microtubule capture by recruiting ACF7 to the plasma membrane of migrating cells.
AuthorsZaoui K, Benseddik K, Daou P, Salaün D, Badache A,
JournalProc Natl Acad Sci U S A
PubMed ID20937854
Microtubules (MTs) contribute to key processes during cell motility, including the regulation of focal adhesion turnover and the establishment and maintenance of cell orientation. It was previously demonstrated that the ErbB2 receptor tyrosine kinase regulated MT outgrowth to the cell cortex via a complex including Memo, the GTPase RhoA, and ... More