Synaptic targeting of N-type calcium channels in hippocampal neurons.
AuthorsMaximov A, Bezprozvanny I,
JournalJ Neurosci
PubMed ID12177192
'N-type calcium (Ca2+) channels play a critical role in synaptic function, but the mechanisms responsible for their targeting in neurons are poorly understood. N-type channels are formed by an alpha(1B) (Ca(V)2.2) pore-forming subunit associated with beta and alpha2delta auxiliary subunits. By expressing epitope-tagged recombinant alpha1B subunits in rat hippocampal neuronal ... More