Polisher ST Membrane Adsorber is a single-use AEX purifier for flow-through polishing of biopharma streams. It reduces HCP, viruses, DNA, and other negatively charged impurities using a Q-functional nonwoven and a guanidinium membrane. The Q layer lowers turbidity and DNA, while the membrane adds capacity, strong viral clearance, and salt tolerance. Available in multiple sizes for seamless scale-up
- The Polisher ST is single use multi-mechanism membrane adsorber which contains a Q-functional anion exchange non woven media and guanidinium functionalized membrane. This product removes residual turbidity, DNA and HCP and provides robust virus clearance for improved downstream/polishing purification.
- Single-use technology as a cost-efficient option to increase biomass production by delivering high purity and yield in the downstream polishing unit operation in therapeutic recombinant protein process in biologically relevant operating conditions
- Replaces downstream AEX polishing column for reduction of HCP and virus in a salt tolerant (ST) manner as a single-use solution
- Provides DNA reduction in a salt tolerant (ST) manner compared with conventional Q-functional AEX resins