A Proteomic Analysis of MCLR-induced Neurotoxicity: Implications for Alzheimer's Disease.
AuthorsLi G, Cai F, Yan W, Li C, Wang J
JournalToxicol Sci
PubMed ID22430071
Cyanobacteria-derived microcystin-leucine-arginine (MCLR), commonly characterized as a hepatotoxin, has recently been found to show neurotoxicity, but the exact mechanism is still unknown. To further our understanding of the neurotoxic effects of MCLR and the mechanisms behind it, we used two-dimensional gel electrophoresis and mass spectrometry analysis to identify global protein ... More