Biologic correlates of a biochemoprevention trial in advanced upper aerodigestive tract premalignant lesions.
AuthorsPapadimitrakopoulou VA, Liu DD, Mao L, Shin DM, El-Naggar A, Ibarguen H, Lee JJ, Hong WK, Hittelman WN,
JournalCancer Epidemiol Biomarkers Prev
PubMed ID12496051
'To identify tissue biomarkers that might be used to assess an individual''s cancer risk and response to chemoprevention, we studied in dysplastic lesions of the larynx and the p.o. cavity, a series of biomarkers extensively used in previous chemoprevention trials, including chromosome polysomy (CP), proliferative status, p53 expression and gene ... More