Subtyping of undifferentiated non-small cell carcinomas in bronchial biopsy specimens.
AuthorsLoo PS, Thomas SC, Nicolson MC, Fyfe MN, Kerr KM,
JournalJ Thorac Oncol
PubMed ID20195168
'The emergence of treatments for non-small cell lung carcinoma (NSCLC) with differential efficacy and toxicity between subtypes has highlighted the importance of specific pathologic NSCLC subtyping. Most NSCLCs are inoperable, and pathologic diagnosis is made only on small tissue samples that are prone to diagnostic inaccuracy. In a substantial proportion ... More
Distribution of p63, cytokeratins 5/6 and cytokeratin 14 in 51 normal and 400 neoplastic human tissue samples using TARP-4 multi-tumor tissue microarray.
AuthorsReis-Filho JS, Simpson PT, Martins A, Preto A, Gärtner F, Schmitt FC,
JournalVirchows Arch
PubMed ID12884041
p63, cytokeratin (CK) 5/6 and CK 14 have been employed in diagnostic pathology as markers of basal, squamous and myoepithelial differentiation in several types of human neoplasms; however, there is scant data on the concurrent expression of these markers in large series of human neoplasms. We analyzed the distribution of ... More