Lynch Syndrome from a surgeon perspective: retrospective study of clinical impact of mismatch repair protein expression analysis in colorectal cancer patients less than 50 years old.
AuthorsBaiocchi GL, Portolani N, Vermi W, Baronchelli C, Gheza F, Zogno C, Scaglia A, Marchina E, Tiberio GA, Giulini SM,
Journal
PubMed ID24533633
In clinical practice, unexpected diagnosis of colorectal cancer in young patients requires prompt surgery, thus genetic testing for Lynch Syndrome is frequently missed, and clinical management may result incorrect. Patients younger than 50 years old undergoing colorectal resection for cancer in the period 1994-2007 were identified (Group A, 49 cases), ... More