CytoScan™ 750K Accel Suite Array and Reagent Kit Bundle

The CytoScan 750K Accel suite of products enables comprehensive whole-genome coverage and superb performance for detecting chromosomal aberrations in a broad range of sample types for constitutional and oncology research applications. It was developed with inputs from cytogenetics globally to provide an intuitive and streamlined platform for rapid and reliable detection of chromosomal aberrations. The complete suite includes the CytoScan 750K Accel array, a reagent kit, user-friendly Chromosome Analysis Suite (ChAS) software, and the GeneChip System 3000 instrument.

This CytoScan 750K Accel Array and Reagent Kit Bundle contains 24 arrays and reagents sufficient for 24 reactions. An amplification kit is not included and will need to be purchased separately.

Features of the CytoScan 750K Accel cytogenetics solution include:

• Two-day workflow from sample to insight
• 100 ng sample DNA requirement, which is 50% less than many other commercially available chromosomal microarrays
• Updated reference model file with challenging sample types (buccal swabs, saliva, products of conception, amnio, CVS) to help generate higher quality results
• Improved coverage in more than 5000 regions across entries in OMIM, RefSeq, ClinGen, and DECIPHER/DDD constitutional databases, with ≥ 90% coverage of ClinGen and DECIPHER databases
• Over 950,000 markers for copy number analysis, including over 250,000 gene-centric SNPs and over 700,000 nonpolymorphic probes
• High-density SNP enabling genome-wide reliable breakpoint detection, heterozygosity determination, 5 Mb loss of heterozygosity (LOH) assay, uniparental disomy (UPD), and consanguinity detection of consistent regions
• A robust and flexible assay designed to help save you time and money, reduce errors, and deliver performance, results, and quality consistent with your research laboratory requirements

Chromosome Analysis Suite Software

Chromosome Analysis Suite (ChAS) Software enables you to view and summarize chromosomal aberrations across the genome. Chromosomal aberrations may include copy number gain or loss, mosaicism, and loss of heterozygosity (LOH). ChAS Software is available at no charge.

CytoScan Automated Interpretation and Reporting solution

Labs may boost discovery yield and simplify variant interpretation with the CytoScan Automated Interpretation and Reporting (AIR) solution that unites ChAS Software with Franklin (by Genoox), an end-toend, artificial intelligence (AI)-driven research solution for automating genetic data research analysis. With CytoScan AIR, users can combine the power of both ChAS and Franklin to augment the visualizations of CNV gains, losses, and LOH with clinical research interpretation information.

CytoScan 750K Accel customer training: prepare for success

New and existing customers are required to receive customer training on CytoScan 750K Accel research assays. Different products are available for purchase based on individual experience levels; please contact your regional dealer for more information. Additionally, please see our CytoScan 750K Accel training kit (available outside of US and Canada only).