Axiom™ UKBBPro™ SwitArray™ 96F

The SwiftArray™ UKBBPro 96F is an Axiom Microarray specifically engineered by and for thought leaders in the human genetics community to address the demands of contemporary genomic research. This comprehensive genotyping solution enables high-throughput, high-value analysis of large sample cohorts, facilitating exploration of complex disease genetics and translational research applications through a single, cost-effective platform.

Features

• Genome-Wide Association Studies (GWAS): Comprehensive analysis capabilities for identifying genetic variants associated with complex traits and diseases across the entire genome
• Pharmacogenomic Markers: Integration of genetic variants that influence drug metabolism, efficacy, and adverse drug reactions to support personalized medicine applications
• Inflammation and HLA Analysis: Specialized modules for examining inflammatory pathways and Human Leukocyte Antigen (HLA) typing, critical for immunogenetics and transplantation compatibility studies
• Exome Sequencing Support: Complete analysis framework for protein-coding regions of the genome, enabling identification of rare variants and functional mutations in disease-relevant genes
• Expression Quantitative Trait Loci (eQTLs): Advanced tools for mapping genetic variants that regulate gene expression levels, facilitating functional genomics research and mechanistic studies
• Human Disease Association: Comprehensive database integration and analytical capabilities for investigating genetic contributions to human pathologies and disease susceptibility
• Multi-Modal Genomic Integration: Unified platform combining multiple genomic data types to provide comprehensive insights into genetic architecture and disease mechanisms

Microarray Genotyping Technology for Comprehensive Genomic Analysis

The microarray platform incorporates intelligent marker selection technology that facilitates the imputation of millions of additional single nucleotide polymorphisms (SNPs) beyond those directly assayed on the array. This computational enhancement significantly expands the genomic coverage and analytical power of the platform without requiring additional laboratory procedures. The genomic content module of each array has been specifically optimized for distinct population groups, ensuring maximum relevance and accuracy for targeted demographic studies. Furthermore, the platform offers complete customization capabilities that allow researchers to tailor the array content to any population represented in the 1000 Genomes Project by incorporating additional markers of their selection, providing unprecedented flexibility for population-specific genomic investigations.