Axiom™ PangenomeCore™ SwitArray™ 96F

Axiom™ SwiftArray™ PangenomeCore Array contains more than 800,000 variants designed for genome-wide research across diverse populations. The array combines comprehensive GWAS coverage with curated content for host genetics, immune response, pharmacogenomics, HLA analysis, and infectious disease research, including SARS-CoV-2. High-density pathway coverage, multi-ethnic optimization, and rapid microarray workflows provide a scalable, cost-effective alternative to whole-genome sequencing for large cohort studies.

• Contains more than 800,000 variants for comprehensive genome-wide genotyping across diverse populations.
• Combines broad GWAS coverage with curated content for host genetics, immune response, pharmacogenomics, and infectious disease research.
• Supports studies of disease susceptibility, severity, therapeutic response, and population genomics, including research on SARS-CoV-2 and other infectious diseases.
• Includes dedicated research modules for host susceptibility, disease severity, and immune response investigations.
• Features dense coverage of biologically relevant signaling pathways, including NF-κB, MAPK, IFN, TNF, Toll-like receptor, NOD-like receptor, AMPK, TGF-β, and apoptosis pathways.
• Incorporates more than 725,000 multi-ethnic GWAS markers to maximize genome-wide coverage and imputation performance.
• Includes markers for HLA and KIR imputation, pharmacogenomics (ADME), eQTLs, exome variants, ClinVar pathogenic variants, miRNA variants, published GWAS hits, and ancestry analysis.
• Provides comprehensive coverage of disease-associated variants related to cardiovascular disease, diabetes, lung function, COPD, asthma, autoimmune disorders, neurological disorders, cancer, and blood phenotypes.
• Supports high-quality imputation across African, Admixed American, East Asian, European, and South Asian populations using optimized multi-ethnic genomic content.
• Enables vaccine research, biomarker discovery, therapeutic target identification, and translational research through integrated immune response and host-pathogen interaction content.
• Developed with contributions from leading researchers, biobanks, and key opinion leaders using peer-reviewed and emerging genomic research.
• Delivers a rapid, scalable, and cost-effective microarray workflow compared with whole-genome sequencing while maintaining comprehensive genomic coverage.

Axiom™ SwiftArray™ PangenomeCore Array is a high-density genotyping microarray designed to support comprehensive genome-wide research across diverse populations. Containing more than 800,000 variants, the array combines broad GWAS coverage with curated genomic content for host genetics, immune response, pharmacogenomics, and infectious disease research. Specialized research modules support investigations into disease susceptibility, severity, therapeutic response, and host-pathogen interactions, including studies of SARS-CoV-2 and other infectious diseases. The array features dense coverage of key immune and inflammatory signaling pathways, HLA and KIR imputation, exome variants, eQTLs, ClinVar pathogenic variants, pharmacogenomic markers, ancestry markers, and published GWAS loci. Optimized for multi-ethnic populations, the platform supports accurate imputation of millions of additional variants while providing a rapid, scalable, and cost-effective alternative to whole-genome sequencing. Developed in collaboration with leading researchers and biobank communities, the Axiom™ SwiftArray™ PangenomeCore Array enables population genomics, biomarker discovery, vaccine and therapeutic research, and large-scale translational genomics studies.