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引用和文献 (4)
Invitrogen™
Leadmium™ 绿色 AM 染料
Molecular Probes™ 专有的 Leadmium™ 绿色 AM 染料为研究人员提供了一种独特的工具，能够以高灵敏度特异性测量细胞内铅和镉水平。虽然存在用于测量溶液中的铅和镉含量的标准测定试剂盒，但独特的 Leadmium™ 绿色了解更多信息
| 货号 | 数量 |
|---|---|
| A10024 | 5 x 50 μg |
货号 A10024
价格（CNY)
2,580.00
飞享价
Ends: 31-Dec-2025
3,472.00共减 892.00 (26%)
Each
数量:
5 x 50 μg
价格（CNY)
2,580.00
飞享价
Ends: 31-Dec-2025
3,472.00共减 892.00 (26%)
Each
Molecular Probes™ 专有的 Leadmium™ 绿色 AM 染料为研究人员提供了一种独特的工具，能够以高灵敏度特异性测量细胞内铅和镉水平。虽然存在用于测量溶液中的铅和镉含量的标准测定试剂盒，但独特的 Leadmium™ 绿色 AM 指示剂专为检测活细胞中的这些有毒环境污染物而设计。
了解有关离子指示剂（包括钙、钾、pH 值和膜电位指示剂）的更多信息›
– 用于细胞内铅和镉含量测量的高度特异性指示剂
– 灵活的形式允许用于多种检测方式—流式细胞分析、荧光显微镜成像以及微孔板读数仪
– 明亮的荧光和对钙的高分辨力，可检测出纳摩尔水平的铅和微摩尔水平的镉
– 采用 488 nm 激光线轻松激发
– Leadmium™ 绿色 AM 染料易于加载，在酯酶切割乙酰氧基甲基基团后能很好地保留在细胞内
了解有关离子指示剂（包括钙、钾、pH 值和膜电位指示剂）的更多信息›
– 用于细胞内铅和镉含量测量的高度特异性指示剂
– 灵活的形式允许用于多种检测方式—流式细胞分析、荧光显微镜成像以及微孔板读数仪
– 明亮的荧光和对钙的高分辨力，可检测出纳摩尔水平的铅和微摩尔水平的镉
– 采用 488 nm 激光线轻松激发
– Leadmium™ 绿色 AM 染料易于加载，在酯酶切割乙酰氧基甲基基团后能很好地保留在细胞内
仅供科研使用。不可用于诊断程序。
规格
检测方法荧光
染料类型基于荧光染料
数量5 x 50 μg
运输条件室温
适用于（设备）荧光显微镜, 流式细胞仪
产品线Leadmium
产品类型染料
Unit SizeEach
内容与储存
在冷冻冰箱（-5°C 至 -30°C）中避光储存。
引用和文献 (4)
引用和文献
Abstract
A new ABC half-transporter in Leishmania major is involved in resistance to antimony.
Journal:
PubMed ID:23716044
The characterization of ABCI4, a new intracellular ATP-binding cassette (ABC) half-transporter in Leishmania major, is described. We show that ABCI4 is involved in heavy metal export, thereby conferring resistance to Pentostam, to Sb(III), and to As(III) and Cd(II). Parasites overexpressing ABCI4 showed a lower mitochondrial toxic effect of antimony by
Increased nuclear thioredoxin-1 potentiates cadmium-induced cytotoxicity.
Journal:Toxicol Sci
PubMed ID:22961094
Cadmium (Cd) is a widely dispersed environmental agent that causes oxidative toxicity through mechanisms that are sensitive to thioredoxin-1 (Trx1). Trx1 is a cytoplasmic protein that translocates to nuclei during oxidative stress. Recent research shows that interaction of Trx1 with actin plays a critical role in cell survival and that
Cellular sequestration of cadmium in the hyperaccumulator plant species Sedum alfredii.
Journal:Plant Physiol
PubMed ID:22025609
Spatial imaging of cadmium (Cd) in the hyperaccumulator Sedum alfredii was investigated in vivo by laser ablation inductively coupled plasma mass spectrometry and x-ray microfluorescence imaging. Preferential Cd accumulation in the pith and cortex was observed in stems of the Cd hyperaccumulating ecotype (HE), whereas Cd was restricted to the
Chemically diverse toxicants converge on Fyn and c-Cbl to disrupt precursor cell function.
Journal:PLoS Biol
PubMed ID:17298174
Identification of common mechanistic principles that shed light on the action of the many chemically diverse toxicants to which we are exposed is of central importance in understanding how toxicants disrupt normal cellular function and in developing more effective means of protecting against such effects. Of particular importance is identifying