ARP(N-(氨基氧基乙酰基)-N'-(D-生物酰基) 肼,三氟乙酸盐)
ARP(<i>N</i>-(氨基氧基乙酰基)-<i>N</i>'-(D-生物酰基) 肼,三氟乙酸盐)
Invitrogen™

ARP(N-(氨基氧基乙酰基)-N'-(D-生物酰基) 肼,三氟乙酸盐)

ARP (Aldehyde-Reactive Probe) is a biotinylated hydroxylamine that reacts with the exposed aldehyde group formed at abasic sites in damaged了解更多信息
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货号数量
A1055010 mg
货号 A10550
价格(CNY)
4,881.00
Each
添加至购物车
数量:
10 mg
价格(CNY)
4,881.00
Each
添加至购物车
ARP (Aldehyde-Reactive Probe) is a biotinylated hydroxylamine that reacts with the exposed aldehyde group formed at abasic sites in damaged DNA. The biotins bound to the abasic sites can then be quantitated with fluorescent or enzyme-conjugated streptavidin complexes. ARP is suitable for use in microplate assays.
仅供科研使用。不可用于诊断程序。
规格
化学反应性羧酸、酮、醛
标签或染料生物素
产品类型ARP
数量10 mg
反应一部分胺、羟胺
运输条件室温
标签类型生物素和其他半抗原
Unit SizeEach
内容与储存
在冷冻冰箱(-5 至 -30°C)中储存。

引用和文献 (18)

引用和文献
Abstract
Optimizing antibody immobilization strategies for the construction of protein microarrays.
Authors:Peluso P, Wilson DS, Do D, Tran H, Venkatasubbaiah M, Quincy D, Heidecker B, Poindexter K, Tolani N, Phelan M, Witte K, Jung LS, Wagner P, Nock S
Journal:Anal Biochem
PubMed ID:12531195
'Antibody microarrays have the potential to revolutionize protein expression profiling. The intensity of specific signal produced on a feature of such an array is related to the amount of analyte that is captured from the biological mixture by the immobilized antibody (the "capture agent"). This in turn is a function ... More
N-t-butyl hydroxylamine, a hydrolysis product of alpha-phenyl-N-t-butyl nitrone, is more potent in delaying senescence in human lung fibroblasts.
Authors:Atamna H, Paler-Martínez A, Ames BN
Journal:J Biol Chem
PubMed ID:10702229
'Alpha-phenyl-N-t-butyl nitrone (PBN), a spin trap, scavenges hydroxyl radicals, protects tissues from oxidative injury, and delays senescence of both normal human lung fibroblasts (IMR90) and senescence-accelerated mice. N-t-butyl hydroxylamine and benzaldehyde are the breakdown products of PBN. N-t-Butyl hydroxylamine delays senescence of IMR90 cells at concentrations as low as 10 ... More
Detection of abasic sites and oxidative DNA base damage using an ELISA-like assay.
Authors:Kow YW, Dare A
Journal:Methods
PubMed ID:11020331
'Reactive oxygen species produce a wide spectrum of DNA damage, including oxidative base damage and abasic (AP) sites. Many procedures are available for the quantification and detection of base damage and AP sites. However, either these procedures are laborious or the starting materials are difficult to obtain. A biotinylated aldehyde-specific ... More
Direct visualization of abasic sites on a single DNA molecule using fluorescence microscopy.
Authors:Hirose T, Ohtani T, Muramatsu H, Tanaka A
Journal:Photochem Photobiol
PubMed ID:12194206
'A new method was developed to allow direct visualization of damaged sites on individual DNA molecules. Fluorescence in situ hybridization on extended DNA molecules was modified to detect a single abasic site. Abasic sites were specifically labeled with a biotinylated aldehyde-reactive probe and fluorochrome-conjugated streptavidin. The light emitted by a ... More
A chemoenzymatic approach toward the rapid and sensitive detection of O-GlcNAc posttranslational modifications.
Authors:Khidekel N, Arndt S, Lamarre-Vincent N, Lippert A, Poulin-Kerstien KG, Ramakrishnan B, Qasba PK, Hsieh-Wilson LC
Journal:J Am Chem Soc
PubMed ID:14692737