Differential roles of migratory and resident DCs in T cell priming after mucosal or skin HSV-1 infection.
AuthorsLee HK, Zamora M, Linehan MM, Iijima N, Gonzalez D, Haberman A, Iwasaki A,
JournalJ Exp Med
PubMed ID19153243
Although mucosal surfaces represent the main portal of entry for pathogens, the mechanism of antigen presentation by dendritic cells (DCs) that patrol various mucosal tissues remains unclear. Instead, much effort has focused on the understanding of initiation of immune responses generated against antigens delivered by injection. We examined the contributions ... More