PIP5K-dependent production of PIP2 sustains microtubule organization to establish polarized transport in the Drosophila oocyte.
AuthorsGervais L, Claret S, Januschke J, Roth S, Guichet A,
JournalDevelopment
PubMed ID18948416
'The attachment of the cytoskeleton to the plasma membrane is crucial in controlling the polarized transport of cell-fate-determining molecules. Attachment involves adaptor molecules, which have the capacity to bind to both the plasma membrane and elements of the cytoskeleton, such as microtubules and actin filaments. Using the Drosophila oocyte as ... More
Quantitative evaluation of signaling events in Drosophila s2 cells.
AuthorsBond D, Primrose DA, Foley E,
JournalBiol Proced Online
PubMed ID18385808
Drosophila activates a robust defense response to gram-negative bacteria through the Immune deficiency (Imd) pathway. Imd signaling proceeds through c-Jun N-terminal Kinase (JNK), NF-kB and caspase modules. The individual signaling modules act in a highly coordinated manner to yield a stereotypical response to infection. While considerable attention has focused on ... More
Dendritic cell-nerve clusters are sites of T cell proliferation in allergic airway inflammation.
AuthorsVeres TZ, Shevchenko M, Krasteva G, Spies E, Prenzler F, Rochlitzer S, Tschernig T, Krug N, Kummer W, Braun A,
JournalAm J Pathol
PubMed ID19179611
Interactions between T cells and dendritic cells in the airway mucosa precede secondary immune responses to inhaled antigen. The purpose of this study was to identify the anatomical locations where dendritic cell-T cell interactions occur, resulting in T cells activation by dendritic cells. In a mouse model of allergic airway ... More
Two distinct distributions of F-actin are present in the hyphal apex of the oomycete Achlya bisexualis.
AuthorsYu YP, Jackson SL, Garrill A
JournalPlant Cell Physiol
PubMed ID15047875
We show that two distinct distributions of F-actin are present in the hyphal apex of the oomycete Achlya bisexualis, that have been chemically fixed with a combination of methylglyoxal and formaldehyde and stained with Alexa phalloidin. In approximately one half of the hyphae examined, an F-actin depleted zone within the ... More
Preparation of Primary Rat Hepatocyte Spheroids Utilizing the Liquid-Overlay Technique.
Authors
JournalCurr Protoc Toxicol
PubMed ID31529797
Dopamine transporter is enriched in filopodia and induces filopodia formation.
Authors
JournalMol Cell Neurosci
PubMed ID25936602
Changes in endolysosomal organization define a pre-degenerative state in the crumbs mutant Drosophila retina.
Authors
JournalPLoS One
PubMed ID31834921
Expansion of Bacteriophages Is Linked to Aggravated Intestinal Inflammation and Colitis.