Shape effects of nanoparticles conjugated with cell-penetrating peptides (HIV Tat PTD) on CHO cell uptake.
AuthorsZhang K, Fang H, Chen Z, Taylor JS, Wooley KL,
JournalBioconjug Chem
PubMed ID18690739
In order to probe the nanoparticle shape/size effect on cellular uptake, a spherical and two cylindrical nanoparticles, whose lengths were distinctively varied, were constructed by the selective cross-linking of amphiphilic block copolymer micelles. Herein, we demonstrate that, when the nanoparticles were functionalized with the protein transduction domain of human immunodeficiency ... More
A circuit for motor cortical modulation of auditory cortical activity.
AuthorsNelson A, Schneider DM, Takatoh J, Sakurai K, Wang F, Mooney R,
Journal
PubMed ID24005287
Normal hearing depends on the ability to distinguish self-generated sounds from other sounds, and this ability is thought to involve neural circuits that convey copies of motor command signals to various levels of the auditory system. Although such interactions at the cortical level are believed to facilitate auditory comprehension during ... More