Lineage-specific DNA methylation in T cells correlates with histone methylation and enhancer activity.
AuthorsSchmidl C, Klug M, Boeld TJ, Andreesen R, Hoffmann P, Edinger M, Rehli M,
JournalGenome Res
PubMed ID19494038
DNA methylation participates in establishing and maintaining chromatin structures and regulates gene transcription during mammalian development and cellular differentiation. With few exceptions, research thus far has focused on gene promoters, and little is known about the extent, functional relevance, and regulation of cell type-specific DNA methylation at promoter-distal sites. Here, ... More