Background:Ventilator associated pneumonia (VAP) remains a common complication in critically ill surgical patients and its diagnosis remains problematic. Exhaled breath contains aerosolized droplets that reflect the lung microbiota. We hypothesized that exhaled breath condensate fluid (EBCF) in hygroscopic condenser humidifier/heat moisture exchange (HCH/HME) filters would contain bacterial DNA that qualitatively ... More
Iron transport through ferroportin is induced by intracellular ascorbate and involves IRP2 and HIF2a.
AuthorsScheers N, Sandberg AS,
Journal
PubMed ID24394537
A few tightly regulated transport proteins mediate iron absorption across the intestinal epithelium. At the basolateral border of intestinal cells there is one identified transporter, ferroportin, for the transfer of intracellular iron to the vascular system. Here, we investigate the effects of ascorbate (vitamin C) on the regulation of ferroportin ... More