Predominance of the SARS-CoV-2 Lineage P.1 and Its Sublineage P.1.2 in Patients from the Metropolitan Region of Porto Alegre, Southern Brazil in March 2021.
AuthorsFranceschi VB, Caldana GD, Perin C, Horn A, Peter C, Cybis GB, Ferrareze PAG, Rotta LN, Cadegiani FA, Zimerman RA, Thompson CE
JournalPathogens
PubMed ID34451453
Almost a year after the COVID-19 pandemic had begun, new lineages (B.1.1.7, B.1.351, P.1, and B.1.617.2) associated with enhanced transmissibility, immunity evasion, and mortality were identified in the United Kingdom, South Africa, and Brazil. The previous most prevalent lineages in the state of Rio Grande do Sul (RS, Southern Brazil), ... More
High-resolution microbiome analysis enabled by linking of 16S rRNA gene sequences with adjacent genomic contexts.
AuthorsKapustina Ž, Medžiune J, Alzbutas G, Rokaitis I, Matjošaitis K, Mackevicius G, Žeimyte S, Karpus L, Lubys A
JournalMicrob Genom
PubMed ID34473015
Sequence-based characterization of bacterial communities has long been a hostage of limitations of both 16S rRNA gene and whole metagenome sequencing. Neither approach is universally applicable, and the main efforts to resolve constraints have been devoted to improvement of computational prediction tools. Here, we present semi-targeted 16S rRNA sequencing (st16S-seq), ... More