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Invitrogen
Human PRKCD (PKC delta), GST Tag Recombinant Protein
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产品信息
A41913
产品规格
种属
Human
Expression System
Baculovirus
氨基酸序列
Full length
标签
GST-tag
分子量
111.8 kDa
分类
Recombinant
类型
Protein
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
See Label
Amount
1 mg
纯化类型
purified
保存液
50mM tris HCl, pH 8, with 15mM glutathione, 100mM NaCl, 20% glycerol, 5mM DTT
内含物
no preservative
保存条件
-80°C, Avoid Freeze/Thaw Cycles
运输条件
Dry ice
产品详细信息
For maximum recovery please spin prior to use. Unless noted below, aliquots of the 5 µg, 10 µg and 20 µg sizes of kinase are not recommended as materials can be used in original packaging until exhausted. For larger sizes, the number of freeze/thaws may be reduced by preparing aliquots, aliquots below 20 µL are not recommended. Please never store a kinase diluted. If properly stored at -80C, this product is guaranteed for 6 months from date of purchase.
Protein Form: Full Length, Recombinant, Active
The gene accession number for PRKCD (PKC delta) is NP_006245.2.
靶标信息
The PKC family of serine/threonine kinases, including PRKCD (PKC delta), is activated intracellularly by signal transduction pathways. In humans, at least 12 different PKC polypeptides have been identified. These isoforms differ in primary structure, tissue distribution, subcellular localization, mode of action in vitro, response to extracellular signals, and substrate specificity. PKC alpha, beta I, beta II, and gamma form the conventional family; their activities are Ca2+- and phospholipid-dependent. Protein kinase C (PKC) can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play distinct roles in cells. The protein encoded by this gene is one of the PKC family members. Studies both in human and mice demonstrate that this kinase is involved in B cell signaling and in the regulation of growth, apoptosis, and differentiation of a variety of cell types. Alternatively spliced transcript variants encoding the same protein have been observed.
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生物信息学
蛋白别名: 1-May; kinase nPKC-delta; KPCD; nPKC-delta; PKCdeltaVIII; Protein kinase C delta type; protein kinase C delta VIII; Tyrosine-protein kinase PRKCD; unnamed protein product
基因别名: ALPS3; CVID9; MAY1; nPKC-delta; PKCD; PRKCD
UniProt ID: (Human) Q05655
Entrez Gene ID: (Human) 5580
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