NGS Exome DNA Panel

The NGS Exome DNA Panel is human exome enrichment panel for hybridization-based capture of genomic regions of interest from amplified, indexed DNA libraries before next-generation sequencing (NGS). The panel has a total target region of 37.6 Mb.

The panel was designed and optimized for comprehensive exome content, uniform enrichment, and sequencing efficiency. Content is curated from major reference databases and includes coding and relevant non-coding regions, supporting exome studies that depend on reproducible coverage and efficient use of sequencing reads.

Key features:

• Human exome panel
• 6 Mb total target region with added coverage of key research content
• Curated content from major reference and research databases, including ClinVar, CCDS, RefSeq, GENCODE, and Ensembl
• Compatible with standard and quick target enrichment workflows
• Integrates with the Thermo Fisher enzymatic fragmentation and target enrichment workflow

Broad exome content with added coverage. Supporting projects that require broad exome interrogation without moving to whole-genome sequencing.

Uniform enrichment and sequencing efficiency. The panel is positioned to deliver exome content with uniform, high-quality coverage and efficient sequencing utilization, helping customers achieve required coverage without excess sequencing.

Workflow integration for exome studies. The panel is used with the standard or quick target enrichment kits and with Target Enrichment Universal Blockers and Target Enrichment Binding & Purification Beads (Air Dry). It fits directly into the Thermo Fisher workflow built around enzymatic fragmentation, indexing and hybridization-based enrichment.