In 1998, an outbreak of acute encephalitis with high mortality rates among pig handlers in Malaysia led to the discovery of a novel paramyxovirus named Nipah virus. A multidisciplinary investigation that included epidemiology, microbiology, molecular biology, and pathology was pivotal in the discovery of this new human infection. Clinical and ... More
Detection of functional platelet-activating factor receptors on human tonsillar B lymphocytes.
AuthorsBastien Y, Toledano BJ, Mehio N, Cameron L, Lamoukhaid B, Renzi P, Hamid Q, Mazer BD,
JournalJ Immunol
PubMed ID10228030
Although platelet-activating factor (PAF) receptors have been found on B lymphoblastoid cell lines, the action of PAF on freshly isolated human B cells has not been clearly demonstrated. Using a sensitive semiquantitative reverse-transcriptase PCR, we have found PAF receptor mRNA expressed by tonsillar B lymphocytes, but little in T lymphocytes. ... More