Neutrophil CD11b, L-selectin and Fc IgA receptors in patients with dermatitis herpetiformis.
AuthorsSmith AD, Streilein RD, Hall RP,
JournalBr J Dermatol
PubMed ID12452859
'The skin lesions found in patients with dermatitis herpetiformis (DH) are characterized by the presence of neutrophils at the dermal papillary tips in areas where the diagnostic cutaneous IgA deposits are found. Although the presence of the skin lesions of DH is known to be associated with gluten-sensitive enteropathy, the ... More
Humoral immune response to mesothelin in mesothelioma and ovarian cancer patients.
AuthorsHo M, Hassan R, Zhang J, Wang QC, Onda M, Bera T, Pastan I,
JournalClin Cancer Res
PubMed ID15897581
Mesothelin is a glycosyl-phosphatidylinositol-anchored glycoprotein present on the cell surface. Mesothelin is a differentiation antigen that is highly expressed on mesothelioma, ovarian cancer, and pancreatic cancer. The existence of a spontaneous humoral immune response to mesothelin in humans has not been fully studied. Here we addressed the issue of whether ... More