Differentiation of embryonic stem cells into oligodendrocyte precursors.
AuthorsJiang P, Selvaraj V, Deng W,
JournalJ Vis Exp
PubMed ID20489683
'Oligodendrocytes are the myelinating cells of the central nervous system. For regenerative cell therapy in demyelinating diseases, there is significant interest in deriving a pure population of lineage-committed oligodendrocyte precursor cells (OPCs) for transplantation. OPCs are characterized by the activity of the transcription factor Olig2 and surface expression of a ... More