Orbitrap™ Excedion™ Pro Mass Spectrometers
Orbitrap™ Excedion™ Pro Mass Spectrometers
Orbitrap™ Excedion™ Pro Mass Spectrometers
Orbitrap™ Excedion™ Pro Mass Spectrometers
Orbitrap™ Excedion™ Pro Mass Spectrometers
Thermo Scientific™

Orbitrap™ Excedion™ Pro Mass Spectrometers

Discover Thermo Scientific™ Orbitrap™ Excedion™ Pro Mass Spectrometers - next generation hybrid mass spectrometers with exceptional performance for proteins, peptides, and small molecules analysis.
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货号型号Fragmentation
BRE725570

Orbitrap Excedion Pro Mass Spectrometer with EASY-ETD ion source for metabolomics, lipidomics, proteomics, and structural biology

Higher Collisional Dissociation (HCD) for b/y ion fragmentation is included as standard.
Electron Transfer Dissociation (ETD) for c/z ion fragmentation is factory installed.

BRE725571Orbitrap Excedion Pro BioPharma Mass Spectrometer

Higher Collisional Dissociation (HCD) for b/y ion fragmentation is included as standard.
Electron Transfer Dissociation (ETD) for c/z ion fragmentation is option at factory install or field upgrade.

BRE0065446EASY-ETD option available at factory install or field upgrade for Orbitrap Excedion Pro Mass Spectrometers.

Electron Transfer Dissociation (ETD) - Fast and sensitive Electron Transfer Dissociation reaction of precursor ion with fluoranthene radical anions (m/z 202) injection into the IRM to generate a series of c/z-fragment ions. EThcD fragmentation enabled by reaccelerating ETD fragment ions into IRM for HCD fragmentation.

BRE725572Orbitrap Excedion Pro Mass Spectrometer for metabolomics, lipidomics, proteomics, and structural biologyHigher Collisional Dissociation (HCD) for b/y ion fragmentation is included as standard. Electron Transfer Dissociation (ETD) for c/z ion fragmentation is optional as a field upgrade.
BRE0065480Field upgrade Electron Transfer Dissociation (ETD)

Fast and sensitive ETD reaction of precursor ion with fluoranthene radical anions (m/z 202) injection into the IRM to generate a series of c/z-fragment ions. EThcD fragmentation enabled by reaccelerating ETD fragment ions into IRM for HCD fragmentation.

货号 BRE725570
价格(CNY)
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型号:

Orbitrap Excedion Pro Mass Spectrometer with EASY-ETD ion source for metabolomics, lipidomics, proteomics, and structural biology

Fragmentation:

Higher Collisional Dissociation (HCD) for b/y ion fragmentation is included as standard.
Electron Transfer Dissociation (ETD) for c/z ion fragmentation is factory installed.

Enhance your research and achieve groundbreaking discoveries with Orbitrap Excedion Pro Hybrid Mass Spectrometers, with models to meet your specific needs.

The Orbitrap Excedion Pro BioPharma Mass Spectrometer delivers extended capabilities for biopharma characterization applications and higher order structural biology with mass detection up to m/z 12,000. In addition, optional fast and sensitive Electron Transfer Dissociation (ETD) and Electron-Transfer/Higher-Energy Collision Dissociation (EThcD) alternative fragmentation can be field or factory installed.

The core model Orbitrap Excedion Pro Mass Spectrometer offers exceptional performance for proteomics with advanced capabilities for sensitive non-targeted metabolomics and lipidomics analysis. Optional fast and sensitive ETD/EThcD can be factory or field installed for proteomics applications.

Elevate your biopharma characterization

  • Detect low abundant Asp/IsoAsp isomerization
  • Detailed structural elucidation: Discern Leucin and Isoleucin isobaric masses with great confidence
  • Top-up the sequence coverage in middle-down analysis with fast radical driven fragmentation

 

Innovate higher-order structure characterization of biomolecules

  • ETD fragmentation option enables near single residue resolution in bottom-up and top-down Hydrogen-Deuterium Exchange (HDX) analysis with high sensitivity for alternative fragmentation ETD in ion routing multipole and combination of EThcD in the ion routing multipole for detection in the Orbitrap mass analyzer
  • Fast and sensitive ETD reaction of precursor ion with fluoranthene radical anions (m/z 202) injection into the IRM to generate a series of c/z-fragment ions. EThcD fragmentation enabled by reaccelerating ETD fragment ions into IRM for HCD fragmentation
  • HDX-based MS offers a comprehensive and novel toolset for the analysis of protein conformation, conformation dynamics, and protein-protein interactions

 

Exceed in proteomics research

  • Accurate quantification with extended dynamic range
  • Hybrid-DIA
  • Deep proteome coverage
  • PTMs analysis with ETD fragmentation
  • Immunopeptidomics with EThcD fragmentation

 

Discovery in metabolomics research

  • Increased sensitivity up to 10x compound dependent
  • Enhanced Dynamic Range (eDR)
  • Increased unknown annotations

 

Simultaneously measure multiple parameters within a single experiment

  • Up to 20 precursor ions per scan

规格
检测下限
  • Full Scan: < 1.5 fg reserpine on column
  • MS2: < 1.5 fg reserpine on column
  • SIM: < 0.8 fg reserpine on column
尺寸(深 x 宽 x 高)29.8 x 21 x 27.6 in. (758 x 535 x 703 mm)
动态范围Up to 5 orders of magnitude intrascan
Fragmentation

Higher Collisional Dissociation (HCD) for b/y ion fragmentation is included as standard.
Electron Transfer Dissociation (ETD) for c/z ion fragmentation is factory installed.

包括
  • 1-point calibration for <3 ppm RMS drift over at least 4 weeks*
  • Internal lock mass calibration for <1 ppm RMS drift over 24 hours* EASY-IC for <1 ppm RMS drift for at least 5 days*
  • Five orders of magnitude intrascan dynamic range* *Under defined conditions
型号

Orbitrap Excedion Pro Mass Spectrometer with EASY-ETD ion source for metabolomics, lipidomics, proteomics, and structural biology

MultiplexingUp to 20 precursor ions per scan
最大分辨率Up to 480,000 (FWHM) at 200 m/z
类型Orbitrap LC-MS
Unit SizeEach