The human GINS complex associates with Cdc45 and MCM and is essential for DNA replication.
AuthorsAparicio T, Guillou E, Coloma J, Montoya G, Méndez J,
JournalNucleic Acids Res
PubMed ID19223333
'The GINS complex, originally discovered in Saccharomyces cerevisiae and Xenopus laevis, binds to DNA replication origins shortly before the onset of S phase and travels with the replication forks after initiation. In this study we present a detailed characterization of the human GINS (hGINS) homolog. Using new antibodies that allow ... More