AuthorsKatrekar D, Moreno AM, Chen G, Worlikar A, Mali P
JournalSci Rep
PubMed ID29483550
'Recombinant adeno-associated viruses (AAVs) are among the most commonly used vehicles for in vivo gene delivery. However, their tropism is limited, and additionally their efficacy can be negatively affected by prevalence of neutralizing antibodies in sera. Methodologies to systematically engineer AAV capsid properties would thus be of great relevance. In ... More