Baculovirus-mediated gene transfer into mammalian cells.
AuthorsBoyce FM, Bucher NL,
JournalProc Natl Acad Sci U S A
PubMed ID8637876
This paper describes the use of the baculovirus Autographa californica multiple nuclear polyhedrosis virus (AcMNPV) as a vector for gene delivery into mammalian cells. A modified AcMNPV virus was prepared that carried the Escherichia coli lacZ reporter gene under control of the Rous sarcoma virus promoter and mammalian RNA processing ... More
BacMam technology and its application to drug discovery.
AuthorsAmes RS, Kost TA, Condreay JP,
JournalExpert Opin Drug Discov
PubMed ID23488908
The recombinant baculovirus/insect cell system was firmly established as a leading method for recombinant protein production when a new potential use for these viruses was revealed in 1995. It was reported that engineered recombinant baculoviruses could deliver functional expression cassettes to mammalian cell types; a system which has come to ... More
Prevention of radiation-induced bystander effects by agents that inactivate cell-free chromatin released from irradiated dying cells.
Authors
JournalCell Death Dis
PubMed ID30442925
Interfacing 3D magnetic twisting cytometry with confocal fluorescence microscopy to image force responses in living cells.
Authors
JournalNat Protoc
PubMed ID28686583
Genome-wide CRISPR screen uncovers a synergistic effect of combining Haspin and Aurora kinase B inhibition.
Authors
JournalOncogene
PubMed ID32300176
Exogenous Expression of Human Protamine 1 (hPrm1) Remodels Fibroblast Nuclei into Spermatid-like Structures.
Authors
JournalCell Rep
PubMed ID26628361
Transcription upregulation via force-induced direct stretching of chromatin.