Optical tracking and detection of immunomagnetically selected and aligned cells.
AuthorsTibbe AG, de Grooth BG, Greve J, Liberti PA, Dolan GJ, Terstappen LW
JournalNat Biotechnol
PubMed ID10585720
We have developed a platform for cell analysis based on immunomagnetic selection and magnetic alignment of cells in combination with an epi-illumination tracking and detection system. Whole blood was labeled with ferromagnetic nanoparticles and fluorescent probes, and placed in a magnetic field in a chamber. Cells labeled with ferromagnetic nanoparticles ... More